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valvular heart disease

n.
1.heart disease caused by stenosis of the cardiac valves and obstructed blood flow or caused by degeneration and blood regurgitation

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    call the shots
    to be in charge, to give orders
    The vice-president is now calling the shots and is in control of the company.



    1.
    The price of petrol went ________ by five pence, which made motorists very angry

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