1. Oh no...
2. That's terrible.
3. Poor you. (Use this to respond to bad situations that are not too serious)
4. I'm so sorry to hear that.
5. I'm sorry for your loss. (Use this only if someone has died)

Fact
The philosopher, ren descartes, who considered himself to be the inventor of the first philosophical principle - cogito ergo sum (i think, therefore, i am), - died while visiting queen kristina in 1649. The castle was very cold and descartes suffered from pneumonia, which killed him.      .. More >>